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Recently denosumab demonstrated a significant delay in the o
2019-06-14
Recently, denosumab demonstrated a significant delay in the onset of detectable bone lesions in men with castration resistant prostate cancer compared to placebo . This could indicate some kind of efficacy of the compound as anticancer agent and consequently an indirect confirmation of the role of R
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Current ASCO recommendations suggest initiating bisphosphona
2019-06-14
Current ASCO recommendations suggest initiating bisphosphonate therapy in myeloma when there is evidence of bone involvement [124]. The optimal duration and frequency of bisphosphonate therapy for myeloma are not well understood and are currently being studied. All randomized, placebo-controlled tri
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Introduction Despite advances in the treatment of early stag
2019-06-14
Introduction Despite advances in the treatment of early stage breast cancer, bone remains the most common site of distant protease inhibitors [1]. The consequences of bone metastases include reduced survival, morbidity, pain and reduced quality of life [2]. While the care of these patients is mult
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BTL-104 br Study limitations br Conflict of interest
2019-06-14
Study limitations Conflict of interest Case report Discussion DFT testing is usually recommended to ensure proper functioning of the ICD/CRT-D and verify that there is no acute lead dislodgement [1,2]. For patients with impaired cardiac function, VF induction and shock delivery can cause
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Effective medical management of cutaneous metastasis
2019-06-14
Effective medical management of cutaneous hydralazine hydrochloride arising from internal malignancy is usually difficult. Systemic chemotherapy and local excision or radiation therapy may be considered. As for metastatic ampulla of Vater cancer, the more recent histological differentiation in inte
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Pregnancies in adolescents year olds and
2019-06-14
Pregnancies in adolescents (10–19-year-olds) and in older women (≥35 years) are hazardous for the mother and the child. Despite an almost universal decline in the adolescent purchase galanin since 1990, adolescent fertility still accounts for 11% of all births worldwide, with 95% of these births oc
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Cepheid s GeneXpert system achieved recognition as a
2019-06-14
Cepheid\'s GeneXpert system achieved recognition as a rapid molecular test to identify active tuberculosis and rifampicin resistance, a marker for multidrug-resistant tuberculosis. So far, more than 13 million Xpert /rifampicin (MTB/RIF) tests have been done worldwide. However, the primary criticism
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Un caso importante de esa
2019-06-14
Un caso importante de esa etapa es el movimiento cocalero, el mismo que decide participar electoralmente pero no logra acuerdo respecto trk receptor la mejor fórmula y se divide en dos grupos distintos. Por un lado, los cocaleros del Valle del río Apurímac, que optan por construir el “instrumento po
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El n mero de ofrece
2019-06-14
El número 62 de ofrece, en una primera sección, tres artículos que se ubican en los campos de la literatura, las revistas culturales y en general las redes intelectuales en América Latina. Lucía Di Salvo León y Patricio Herrera González, en “¿Una poética del exilio? La revista y el exilio republica
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In recent years the impact that food production and
2019-06-13
In recent years, the impact that food production and consumption have had on the environment has received increasing international attention. Some food production practices and consumption behaviours are putting the environment under a great stress, contributing to climate change. The food sector ac
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br Bilbao en el cruce entre
2019-06-13
Bilbao, en el cruce entre anticolonialismo y socialismo de las periferias Como adelantamos arriba, el presente artículo reconstruye una etapa poco conocida de la vida de este autor sorprendente. El acercamiento que presentamos trata de reconstruir los contextos intelectuales del exilio parisino d
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Introduction Acute erythroleukemia AEL is a
2019-06-13
Introduction Acute erythroleukemia (AEL) is a rare subtype of acute myeloid leukemia (AML), accounting for 3–5% of all AML cases. It is characterized by the expansion of erythroblasts in the bone marrow (BM). Its clinical presentation often resembles myelodysplastic syndromes (MDS), both in terms o
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br Materials and methods Eculizumab levels were measured
2019-06-13
Materials and methods Eculizumab levels were measured at Cambridge Biomedical using a manual ELISA method in which the microtitre plates are coated with C5, then blocked. Standards, controls, and unknowns were added. After incubation and washing, mouse anti-human IgG4 horseradish peroxidase (HRP)
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br Case report In July
2019-06-12
Case report In July 2010, a 64-year-old man visited the outpatient clinic of National Taiwan University Hospital due to progressive enlargement of right submandibular mass for months. A nasopharyngeal tumor was found by fiber optic exam, and biopsy showed a non-keratinizing undifferentiated carci
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br Conclusion br Conflict of interest br
2019-06-12
Conclusion Conflict of interest Introduction Dermatofibrosarcoma protuberans (DFSP) is a rare soft-tissue neoplasm that was first identified by Taylor, RW in 1890. It was then described in 1924 by Darier, J and Ferrand, M as a progressive recurrent dermatofibroma, and was later termed DFSP
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