• MRS 1220 receptor Introduction Cytochrome P CYP A is the

  2020-08-10

  

  Introduction Cytochrome P450 (CYP)3A is the most important enzyme involved in the metabolism of 30–40% of currently prescribed drugs [1]. The MRS 1220 receptor level and activity of CYP3A show large intra- and inter-individual variability, which contributes to unpredictable drug response and toxic

• The data presented above clearly

  2020-08-10

  

  The data presented above clearly indicate an important role of eIF4E for the nucleocytoplasmic transport of the human iNOS mRNA. To analyze the sequence elements of the iNOS mRNA that are important for this eIF4E-mediated transport we performed transient transfection experiments using constructs con

• The UI compo http www apexbt com media

  2020-08-10

  

  The UI components used in our proposal are called COTSgets, from COTS (Commercial Off-The-Shelf) [28] and gadgets (understood as any software that can work alone or as a piece of the architecture). A COTS component is any coarse-grained component developed by third parties available for building mor

• Three new trans P Hs AlP

  2020-08-10

  

  Three new trans-P4Hs (AlP4H, MiP4H and ScP4H) discovered by a genome mining approach in this study were all located in branch A containing DaP4H sequence. Although another three candidates from Amycolatopsis mediterranei, Bradyrhizobium sp. ORS285 and O. indicum were successfully expressed as solubl

• The classification of CK substrates based on

  2020-08-10

  

  The classification of CK2 substrates based on active enzyme subunit composition provides a framework for understanding the regulatory function of CK2β subunit. However, few experiments exist that functionally explore such classification [17], [18], [19], [20], [21], [22], [23]; this reflects practi

• The phenolic hydroxyl group of ezetimibe

  2020-08-10

  

  The phenolic hydroxyl group of ezetimibe tolerated various structural modifications (disaccharide, carboxyalkyl and glucuronide) that retained inhibitory activity.13, 14, 15 We conjugated glycylglycine to phenolic hydroxyl group and synthesized ten 1H-pyrrole-2,5-dione derivatives 14a-j successfully

• br Materials and methods br Results br Discussion The

  2020-08-10

  

  Materials and methods Results Discussion The nitric oxide generating enzymes of the NOS family comprise three isoforms: nNOS, iNOS and eNOS [31]. Expression of eNOS is mainly found in endothelial resveratrol where it physically promotes vasodilation [32]. Conversely, evidence also indicates

• br Materials and methods BAECs

  2020-08-10

  

  Materials and methods BAECs (CAB30405, Toyobo Life Science, Osaka, Japan) were cultured in Dulbecco’s Modified Eagle Medium supplemented with 10% Fetal Bovine Serum (04-001-1A-US, Biological Industries, Kibbutz Beit Haemek, Israel) and 1% antibiotic-antifungal agent containing 10,000-μg/mL penici

• To assess whether the described cooperation between the

  2020-08-10

  

  To assess whether the described cooperation between the EGFR and FGFR receptors was relevant at the clinical level, we determined the effect on progression-free survival of FGFR1 expression in patients with adenocarcinoma who were receiving erlotinib or gefitinib. As we had observed EGFR-FGFR1 coope

• br Acknowledgments This work was supported by Grants from

  2020-08-10

  

  Acknowledgments This work was supported by Grants from the National Research Foundation (2010-0000782) and the National Center for GM Crops (PJ008152) of the Next Generation BioGreen 21 Program funded by the Rural Development Administration, Republic of Korea, to W.T.K. Introduction Ubiquityl

• br Acknowledgments This work is supported by grants from the

  2020-08-08

  

  Acknowledgments This work is supported by grants from the Singapore National Medical Research Council (R-713-000-181-511) and the Ministry of Education (R-713-000-169-112) and by the National Research Foundation Singapore and the Singapore Ministry of Education under its Research Centres of Excel

• In this study the ASTM C

  2020-08-08

  

  In this study, the ASTM C1260 and ASTM C1567 test methods were followed to conduct the ASR tests. Three mortar bars were prepared using three types of RHA (600-RHA, 150-RHA, and 44-RHA) and CFA. To prepare the mortar bars, the OPC was replaced by each type of RHA for 10% and 20%, respectively by wei

• Different supplementary cementitious materials SCMs such as

  2020-08-08

  

  Different supplementary cementitious materials (SCMs) such as fly ash, silica fume, and slag can be used to lessen ASR problem. Use of SCMs as partial replacement of cement reduces the alkali content of cement [1]. In addition, the porosity of the concrete can be enhanced by SCMs that will reduce th

• To further validate OsSCE gene function

  2020-08-07

  

  To further validate OsSCE1 gene function in relation to drought stress, we established OsSCE1-OX (overexpressed) and OsSCE1-KD (knockdown) transgenic rice plants. Drought stress analysis using PEG6000 showed the selected OsSCE1-OX line (S15.1) had a lower tolerance to drought stress than WT plants (

• Analyses of upstream promotor sequences of cysteine protease

  2020-08-06

  

  Analyses of upstream promotor sequences of cysteine proteases and phytocystatins and interaction between transcription factors are the initial step to understanding the regulatory mechanisms that control their gene expression. Analyses of the expression levels of TFs and their targets confirm this i

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