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br Discussion To our knowledge we
2019-06-28
Discussion To our knowledge, we report for the first time t(8;21) acute myeloid leukemia presenting as severe aplastic anemia. t(8;21)(q22;q22) is present in 5–10% of all AMLs, and includes variety of subtypes with varying pathology, and clinical presentations, ranging from circulating blast in p
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The congruence between BrS and ERS
2019-06-28
The congruence between BrS and ERS with respect to clinical manifestations and response to therapy lends further support to the repolarization hypothesis. Using an experimental model of ERS, Koncz et al. [30]. recently provided evidence in support of the hypothesis that, similar to the mechanism ope
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Babies and children feature heavily in this August
2019-06-28
Babies and children feature heavily in this August issue of , as well they should at a time when unfinished agendas are top of the agenda. In its 2014 report on the , released on July 7, the UN described the under-5 mortality goal as “slipping away from achievement by 2015”. The research and opinion
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br We welcome the efforts by Robert Cohen and colleagues
2019-06-28
We welcome the efforts by Robert Cohen and colleagues to promote country-specific targets for post-2015 health goals. Publications from the Consortium of Universities for Global Health () conference included a welcome focus on the building of effective global health education programmes. Histor
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Introduction Personalized medicine is the major goal
2019-06-27
Introduction Personalized medicine is the major goal of translational research in the post-genomic era. Numerous biomarkers have been identified by genomic or proteomic approach that can reclassify the disease PRIMA-1 weight and predict clinical outcome. However, to define a specific disease phenot
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Ad Mapu lleg a convertirse
2019-06-27
Ad Mapu llegó Fmoc-Phe-OPfp of convertirse en un gran referente que contribuyó al fortalecimiento de la conciencia de la situación mapuche, así lo explica Víctor Toledo al mencionar que es en este momento cuando aparece bosquejada la autodeterminación como propuesta del pueblo mapuche, y recuerda la
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The primary tool in the pharmacological management of PTSD
2019-06-27
The primary tool in the pharmacological management of PTSD is the use of selective serotonin reuptake inhibitors [55,56], but positive response rates are generally limited. In addition, non-pharmacological treatment such as CBT has been shown to be effective for PTSD [57]. Psychological distress
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br Other drugs Overdose of diphenhydramine an H histamine re
2019-06-27
Other drugs Overdose of diphenhydramine (an H1 histamine receptor antagonist) is reported to induce a BrS phenotype [58,59]. Antihistamines are known to cause QT prolongation secondary to IKr inhibition. Cocaine is known to block the sodium TOK-001 and thus to unmask a BrS phenotype [60]. Alcoho
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The CONNECT trial conducted by Crossley et
2019-06-27
The CONNECT trial conducted by Crossley et al. [22] was also a multicenter, prospective, randomized evaluation of wireless RM, which included 1997 patients implanted with ICDs or CRT-Ds. They were randomly assigned to the remote or in-office groups and followed up for 15 months. The median time from
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Another recent study also concluded that presence of
2019-06-27
Another recent study also concluded that presence of EMD at diagnosis, rather than any treatment modalities ever used, was the only significant predictor of extramedullary recurrence. This finding suggests that the development of EMD, even during treatment, may possibly reflect different tumor biolo
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br Alternans and arrhythmogenesis in different
2019-06-27
Alternans and arrhythmogenesis in different clinical conditions APD alternans, whether spatially concordant or discordant, can produce arrhythmias. For example, spatially concordant alternans themselves can produce 2:1 conduction block, thereby initiating re-entry [48]. Nevertheless, discordant a
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Ser entonces la fotograf a la Marcha de los claveles
2019-06-27
Será entonces la fotografía la Marcha de los claveles rojos la consolidación del objetivo estético de Calanchina. Dicha imagen fue tomada en blanco y negro y cetp inhibitors el instante justo donde un centenar de hombres y mujeres, reunidos frente al edificio de la Policía Nacional de Guatemala, de
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In Jillian Pintye and colleagues from the Partners
2019-06-27
In Jillian Pintye and colleagues from the Partners PrEP study team present one of the largest and most comprehensive analyses of syphilis incidence in men and women and the effect of male circumcision. The investigators followed 4716 HIV-1 serodiscordant couples, of whom roughly 50% of the men were
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Confluye aqu en su literalidad en
2019-06-27
Confluye aquí, en su literalidad, en su capacidad para evocar cierta “representación pura y simple de lo real”, esa retórica del cuerpo Loxapine Succinate la que hice referencia más arriba. “Cuerpo-texto que destruye el cuerpo-carne pero se monta en él para transformarlo, para sustituirlo”, en la Hi
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Para Galtung se evidencia que
2019-06-27
Para Galtung, se evidencia que el concepto de violencia tiene una triple dimensión: directa, estructural y cultural. Cuando surgen estas tres dimen siones se llama violencia Palifosfamide la afrenta evitable a las necesidades humanas. Así: En cuanto al marco teórico, se utilizan distintos enfoques
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